Synovate HA® Liquid Sodium Hyaluronate Synovate HA® delivers high molecular weight sodium hyaluronate in an easy-to-administer liquid. Equine athletes are prone to injury. Certain injuries happen quickly but others are a result of cumulative wear and tear. Hyaluronic acid (HA) plays a vital role in maintaining the health of connective tissue and optimizing normal joint function. Synovate HA® may assist with supporting equine athletes through the rigors of training and competition. Owners and trainers of high-performance horses rely on intra-articular, intravenous, or oral HA to help protect their horses' joints. Manage Joints Proactively Synovate HA® provides horses with a safe, easily absorbed, and easy-to-use form of sodium hyaluronate. The core ingredient, HA, is a naturally occurring substance found in various connective tissues in the horse's body. HA contributes significantly to maintenance of cartilage health and elasticity, joint fluid viscoelasticity, and lubrication of the entire joint mechanism. In addition, HA has anti-inflammatory properties, especially useful for high-motion joints such as those in equine limbs. The horse maintains considerable reservoirs of HA within its body, yet as horses mature and more athletic demands are placed on them inflammation leads to breakdown of HA in the joint fluid. The loss of HA leads to lower viscoelasticity in the joint fluid and further inflammation, which can damage cartilage and make the joint disease worse. Therefore, it is desirable to manage joint care proactively with Synovate HA®. Superior Biological Activity Researchers have identified differences in biological activities for HA of different molecular weights. HA with a high molecular weight (more than 500,000 daltons) has the greatest biological response. Further, high molecular weight HA created from microbial fermentation, such as Synovate HA®, has the greatest likelihood for matching the known attributes of native HA found in the horse's body. To support your horse's joints, choose Synovate HA®. Source: Fermentation-derived product from nonanimal substrates Molecular weight: 1-1.25 million daltons Concentration 200 mg of hyaluronic acid (sodium) per ounce (30 mL) Feeding Directions Maintenance: Give ½ ounce (15 mL) per 1100-lb (500-kg) horse per day in feed or orally. Loading or precompetition (optional): Give 1 ounce (30 mL) per 1100-lb (500-kg) horse in feed or orally once daily for 7-10 days.